The global wine industry faces multiple problems, including water scarcity, climate change, rising energy prices, and increasing concerns about chemical exposure. Sustainable development in the winery industry is associated with product innovation, higher sustainable competitive advantage, and business performance. Winery businesses aim to achieve sustainability by ensuring they leave the land in good condition for the next generation. Sustainability initiatives are expensive to implement, prompting businesses only to pursue those activities considered necessary to comply with the regulations. This chapter aims to illustrate how the wine industry can incorporate the triple-bottom-line aspects, including environmental, social, and economic sustainability dimensions to diagnose sustainability issues linked to the sector and develop and execute appropriate policies and actions to achieve sustainability goals.