In today's society, it is widely considered that knowledge is the main tool for economic success. Knowledge Management (KM) is the science and activity that analyses and develops that success. However, the level of implementation of KM in order to unlock the developmental potential of knowledge in companies is widely varying between industrial sectors. A decade ago we investigated KM implementation in logistics companies relating investments into knowledge and returns from those investments by means of multivariate regression. Results from this empirical impact study showed a contradiction between the role of knowledge and the implementation of KM in this sector. Since then, society, global economies and companies have developed further; the logistics sector is facing a lot of new challenges. Therefore, we think it is time to repeat the study. Against this background, the paper presents a methodology to be implemented in a multinational and cross-cultural study addressing the implementation of knowledge management in the logistic sector. Based upon a review on literature and statistics the paper puts together ideas from different fields (KM, logistics and Human Resource Development) to build a new framework of analysis. The scientific interest and importance of the paper is twofold: first it develops the concept of national, cross cultural and comparative KM; second, it presents a methodology ready to be used and tested. Main focus is put on comparing KM situation in logistics companies ten years ago and now, identifying changes and their drivers, and understanding influences like country, culture or state of economic development.